pip install xtiff

to_tiff(img, file, image_name=None, image_date=None, channel_names=None, description=None, 
        profile=TiffProfile.OME_TIFF, big_endian=None, big_tiff=None, big_tiff_threshold=4261412864, 
        compression_type=None, compression_level=0, pixel_size=None, pixel_depth=None, 
        interleaved=True, software='xtiff', ome_xml_fun=get_ome_xml, **ome_xml_kwargs)


img: The image to write, as xarray DataArray or numpy-compatible data structure.
    Supported shapes:
    - (y, x),
    - (c, y, x)
    - (z, c, y, x)
    - (t, z, c, y, x)
    - (t, z, c, y, x, s)
    Supported data types:
    - any numpy data type when using TiffProfile.TIFF
    - uint8, uint16, float32 when using TiffProfile.IMAGEJ (uint8 for RGB images)
    - bool, int8, int16, int32, uint8, uint16, uint32, float32, float64 when using TiffProfile.OME_TIFF

file: File target supported by tifffile TiffWriter, e.g. path to file (str, pathlib.Path) or binary stream.

image_name: Image name for OME-TIFF images. If True, the image name is determined using the DataArray name or
    the file name (in that order); if False, the image name is not set. If None, defaults to the behavior for True
    for named DataArrays and when the file path is provided, and to the behavior of False otherwise. Only relevant
    when writing OME-TIFF files, any value other than None or False will raise a warning for other TIFF profiles.

image_date: Date and time of image creation in '%Y:%m:%d %H:%M:%S' format or as datetime object. Defaults to
    the current date and time if None. Note: this does not determine the OME-XML AcquisitionDate element value.

channel_names: A list of channel names. If True, channel names are determined using the DataArray channel
    coordinate; if False, channel names are not set. If None, defaults to the behavior for True for DataArrays when
    writing multi-channel OME-TIFFs, and to the behavior for False otherwise. Only relevant when writing
    multi-channel OME-TIFF files, any value other than None or False will raise a warning for other TIFF profiles.

description: TIFF description tag. Will default to the OME-XML header when writing OME-TIFF files. Any value
    other than None will raise a warning in this case.

profile: TIFF specification of the written file.
    Supported TIFF profiles:
    - TIFF (no restrictions apply)
    - ImageJ (undocumented file format that is supported by the ImageJ software)
    - OME-TIFF (Open Microscopy Environment TIFF standard-compliant file format with minimal OME-XML header)

big_endian: If true, stores data in big endian format, otherwise uses little endian byte order. If None, the
    byte order is set to True for the ImageJ TIFF profile and defaults to the system default otherwise.

big_tiff: If True, enables support for writing files larger than 4GB. Not supported for TiffProfile.IMAGEJ.

big_tiff_threshold: Threshold for enabling BigTIFF support when big_tiff is set to None, in bytes. Defaults
    to 4GB, minus 32MB for metadata.

compression_type: Compression algorithm, see tifffile.TIFF.COMPRESSION() for available values. Compression is
    not supported for TiffProfile.IMAGEJ. Note: Compression prevents from memory-mapping images and should therefore
    be avoided when images are compressed externally, e.g. when they are stored in compressed archives.

compression_level: Compression level, between 0 and 9. Compression is not supported for TiffProfile.IMAGEJ.
    Note: Compression prevents from memory-mapping images and should therefore be avoided when images are compressed
    externally, e.g. when they are stored in compressed archives.

pixel_size: Planar (x/y) size of one pixel, in micrometer.

pixel_depth: Depth (z size) of one pixel, in micrometer. Only relevant when writing OME-TIFF files, any value
    other than None will raise a warning for other TIFF profiles.

interleaved: If True, OME-TIFF images are saved as interleaved (this only affects OME-XML metadata). Always
    True for RGB(A) images (i.e., S=3 or 4) - a warning will be raised if explicitly set to False for RGB(A) images.

software: Name of the software used to create the file. Must be 7-bit ASCII. Saved with the first page only.

ome_xml_fun: Function that will be used for generating the OME-XML header. See the default implementation for
    reference of the required signature. Only relevant when writing OME-TIFF files, ignored otherwise.

ome_xml_kwargs: Optional arguments that are passed to the ome_xml_fun function. Only relevant when writing
    OME-TIFF files, will raise a warning if provided for other TIFF profiles.